Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study.

doi:10.1016/S1470-2045(21)00603-3

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Article

Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study.

The Lancet. Oncology - 1 Jan 2022

Trépo Eric, Caruso Stefano, Yang Jie, Imbeaud Sandrine, Couchy Gabrielle, Bayard Quentin, Letouzé Eric, Ganne-Carrié Nathalie, Moreno Christophe, Oussalah Abderrahim, Féray Cyrille, Blanc Jean Frédéric, Clément Bruno, Hillon Patrick, Boursier Jérôme, Paradis Valérie, Calderaro Julien, Gnemmi Viviane, Nault Jean-Charles, Guéant Jean-Louis, Devière Jacques, Archambeaud Isabelle, Vitellius Carole, Turlin Bruno, Bronowicki Jean-Pierre, Gustot Thierry, Sutton Angela, Ziol Marianne, Nahon Pierre, Zucman-Rossi Jessica

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma is a frequent consequence of alcohol-related liver disease, with variable incidence among heavy drinkers. We did a genome-wide association study (GWAS) to identify common genetic variants for alcohol-related hepatocellular carcinoma. METHODS: We conducted a two-stage case-control GWAS in a discovery cohort of 2107 unrelated European patients with alcohol-related liver disease...

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PMID: 34902334
DOI: 10.1016/S1470-2045(21)00603-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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