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Article

The cellular SFPQ protein as a positive factor in the HIV-1 integration.

Biochimie - 1 Jul 2024

Kikhai Тatiana, Agapkina Yulia, Silkina Maria, Prikazchikova Tatiana, Gottikh Marina

Abstract excerpt

The cellular SFPQ protein is involved in several stages of the HIV-1 life cycle, but the detailed mechanism of its involvement is not yet fully understood. Here, the role of SFPQ in the early stages of HIV-1 replication has been studied. It is found that changes in the intracellular level of SFPQ affect the integration of viral DNA, but not reverse transcription, and SFPQ is a positive factor of integration. A...

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Identifiers

PMID: 38373651
DOI: 10.1016/j.biochi.2024.02.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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