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Article

Shared genetic architecture between hypothyroidism and rheumatoid arthritis: A large-scale cross-trait analysis.

Molecular immunology - 1 Apr 2024

Liu Ruiyan, Shang Xin, Fu Yu, Wang Ying, Wang Ping, Yan Shuxun

Abstract excerpt

BACKGROUND: In recent years, mounting evidence has indicated a co-morbid relationship between hypothyroidism and rheumatoid arthritis (RA), however, the shared genetic factors underlying this association remain unclear. This study aims to investigate the common genetic architecture between hypothyroidism and RA. METHODS: Genome-wide association study (GWAS) summary statistics from recently published studies were...

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Share to Arthritis, Rheumatoid
Share to TYK2 gene
Share to Genetic Loci

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Hypothyroidism

Share to Polymorphism, Single Nucleotide

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Source

Identifiers

PMID: 38368726
DOI: 10.1016/j.molimm.2024.02.002

Genes

PTPN22
TYK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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