Article
Novel associations for hypothyroidism include known autoimmune risk loci.
PloS one - 1 Jan 2012
Eriksson Nicholas, Tung Joyce Y, Kiefer Amy K, Hinds David A, Francke Uta, Mountain Joanna L, Do Chuong B
Abstract excerpt
Hypothyroidism is the most common thyroid disorder, affecting about 5% of the general population. Here we present the current largest genome-wide association study of hypothyroidism, in 3,736 cases and 35,546 controls. Hypothyroidism was assessed via web-based questionnaires. We identify five genome-wide significant associations, three of which are well known to be involved in a large spectrum of autoimmune...
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