Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel insight into the aetiology of rheumatoid arthritis gained by a cross-tissue transcriptome-wide association study.

RMD open - 1 Sept 2022

Ni Jing, Wang Peng, Yin Kang-Jia, Yang Xiao-Ke, Cen Han, Sui Cong, Wu Guo-Cui, Pan Hai-Feng

Abstract excerpt

BACKGROUND: Although genome-wide association studies (GWASs) have identified more than 100 loci associated with rheumatoid arthritis (RA) susceptibility, the causal genes and biological mechanisms remain largely unknown. METHODS: A cross-tissue transcriptome-wide association study (TWAS) using the unified test for molecular signaturestool was performed to integrate GWAS summary statistics from 58 284 individuals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Bioinformatics and Genomic Networks

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Causality

Share to Genetic Associations and Epidemiology

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Rheumatoid Arthritis Research and Therapies

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 37582060
DOI: 10.1136/rmdopen-2022-002529
PMCID: PMC9462377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel insight into the aetiology of rheumatoid arthritis gained by a cross-tissue transcriptome-wide association study.PMID 37582060Read ↗

Synovial transcriptome-wide association study implicates novel genes underlying rheumatoid arthritis riskSemantic proximity Read ↗

Synovial transcriptome-wide association study implicates novel genes underlying rheumatoid arthritis risk.Semantic proximity Read ↗

Integrative Analysis of Transcriptome-Wide Association Study and Gene-Based Association Analysis Identifies Candidate Genes Associated With Juvenile Idiopathic ArthritisSemantic proximity Read ↗

Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritisSemantic proximity Read ↗

Large-scale meta-analysis across East Asian and European populations updated genetic architecture and variant-driven biology of rheumatoid arthritis, identifying 11 novel susceptibility loci.Semantic proximity Read ↗

Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis.Semantic proximity Read ↗

Linking of genetic risk variants to disease-specific gene expression via multi-omics studies in rheumatoid arthritis.Semantic proximity Read ↗

Shared genetic architecture between hypothyroidism and rheumatoid arthritis: A large-scale cross-trait analysis.Semantic proximity Read ↗

Integrative analysis highlighted susceptibility genes for rheumatoid arthritis.Semantic proximity Read ↗

Integrated analysis of single-cell RNA-seq, bulk RNA-seq, Mendelian randomization, and eQTL reveals T cell-related nomogram model and subtype classification in rheumatoid arthritisSemantic proximity Read ↗

Identifying shared genetic loci and common risk genes of rheumatoid arthritis associated with three autoimmune diseases based on large-scale cross-trait genome-wide association studies.Semantic proximity Read ↗

Genetics of rheumatoid arthritis contributes to biology and drug discovery.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.