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Article

Hypothyroidism and rheumatoid arthritis: a two-sample Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2023

Gao Yang, Fan Zheng-Rui, Shi Fang-Yuan

Abstract excerpt

Background: Meta-analysis of genome-wide association studies (GWAS) data showed that the relationship between hypothyroidism and rheumatoid arthritis (RA) risk remains under debate. This study is conducted to test the causal relationship of hypothyroidism and RA. Methods: A two-sample Mendelian randomization (TSMR) analysis was employed to estimate the causality of hypothyroidism and rheumatoid arthritis in...

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Arthritis, Rheumatoid
Genome-Wide Association Study
Hypothyroidism
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37324262
DOI: 10.3389/fendo.2023.1179656
PMCID: PMC10262846

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