Article
Prediction and integration of metabolite-protein interactions with genome-scale metabolic models.
Metabolic engineering - 1 Mar 2024
Habibpour Mahdis, Razaghi-Moghadam Zahra, Nikoloski Zoran
Abstract excerpt
Metabolites, as small molecules, can act not only as substrates to enzymes, but also as effectors of activity of proteins with different functions, thereby affecting various cellular processes. While several experimental techniques have started to catalogue the metabolite-protein interactions (MPIs) present in different cellular contexts, characterizing the functional relevance of MPIs remains a challenging...
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