Computing the functional proteome: recent progress and future prospects for genome-scale models.

Abstract excerpt

Constraint-based models enable the computation of feasible, optimal, and realized biological phenotypes from reaction network reconstructions and constraints on their operation. To date, stoichiometric reconstructions have largely focused on metabolism, resulting in genome-scale metabolic models (M-Models). Recent expansions in network content to encompass proteome synthesis have resulted in models of metabolism...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Expression
• Share to Genome
• Share to Models, Biological