Article

A Mechanistic Model for Genome-Scale Estimations of Metabolic Activity

2021-01-14

Abstract excerpt

In the last decade, different omic technologies have experiences an exponential technological advancement. However, metabolomics has not followed a similarly vertiginous improving improvement and are far from genomics or transcriptomics in terms of throughput, cost and even accuracy. Therefore, genome-scale in-silico methodologies to estimate metabolic activities from genomic data constitute an active field. The s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f7b460ff-7394-54c8-b6b2-ab1773703604
DOI: 10.20944/preprints202101.0280.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Mechanistic Model for Genome-Scale Estimations of Metabolic ActivityDOI 10.20944/preprints202101.0280.v1Read

Metabolic networks: how to identify key components in the regulation of metabolism and growth.Semantic proximity Read

Identification and Integration of Key-Metabolic Reactions from Untargeted MetabolomicsSemantic proximity Read

INTEGRATE: Model-based multi-omics data integration to characterize multi-level metabolic regulationSemantic proximity Read

Differential metabolic activity and discovery of therapeutic targets using summarized metabolic pathway modelsSemantic proximity Read

Simulating Metabolic Pathways to Enhance Interpretations of Metabolome Genome-Wide Association StudiesSemantic proximity Read

Exploring the Genetic Landscape of Metabolic Phenotypes with MetaboSignal.Semantic proximity Read

MetENP/MetENPWeb: An R package and web application for metabolomics enrichment and pathway analysis in Metabolomics WorkbenchSemantic proximity Read

What does your cell really do? Model-based assessment of mammalian cells metabolic functionalities using omics dataSemantic proximity Read

A new genome-scale model enables prediction of cancer metabolic dependenciesSemantic proximity Read

Metabolome 2.0: quantitative genetics and network biology of metabolic phenotypes.Semantic proximity Read

A network-based approach for predicting key enzymes explaining metabolite abundance alterations in a disease phenotype.Semantic proximity Read

Cancer metabolic subtypes and their association with molecular and clinical featuresSemantic proximity Read