Article
CBFA: phenotype prediction integrating metabolic models with constraints derived from experimental data.
BMC systems biology - 3 Dec 2014
Carreira Rafael, Evangelista Pedro, Maia Paulo, Vilaça Paulo, Pont Marcellinus, Tomb Jean-François, Rocha Isabel, Rocha Miguel
Abstract excerpt
BACKGROUND: Flux analysis methods lie at the core of Metabolic Engineering (ME), providing methods for phenotype simulation that allow the determination of flux distributions under different conditions. Although many constraint-based modeling software tools have been developed and published, none provides a free user-friendly application that makes available the full portfolio of flux analysis methods. RESULTS:...
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