Article
Effect of molnupiravir on SARS-CoV-2 evolution in immunocompromised patients: a retrospective observational study.
The Lancet. Microbe - 1 May 2024
Fountain-Jones Nicholas M, Vanhaeften Robert, Williamson Jan, Maskell Janelle, Chua I-Ly J, Charleston Michael, Cooley Louise
Abstract excerpt
INTRODUCTION: Continued SARS-CoV-2 infection among immunocompromised individuals is likely to play a role in generating genomic diversity and the emergence of novel variants. Antiviral treatments such as molnupiravir are used to mitigate severe COVID-19 outcomes, but the extended effects of these drugs on viral evolution in patients with chronic infections remain uncertain. This study investigates how...
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