Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations

28 Dec 2023

Abstract excerpt

One mechanism of variant formation may be evolution during long-term infection in immunosuppressed people. To understand the viral phenotypes evolved during such infection, we tested SARS-CoV-2 viruses evolved from an ancestral B.1 lineage infection lasting over 190 days post-diagnosis in an advanced HIV disease immunosuppressed individual. Sequence and phylogenetic analysis showed two evolving sub-lineages, with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 epidemiological studies
Share to SARS-CoV-2 and COVID-19 Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38361824
DOI: 10.1093/ve/vead075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutationsPMID 38361824Read ↗

Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants.Semantic proximity Read ↗

SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunitySemantic proximity Read ↗

Extensive Intra-host evolution and T cell escape by SARS-CoV-2 in a 2.5-year persistent infection of an immunocompromised hostSemantic proximity Read ↗

Intra-Host Evolution Analyses in an Immunosuppressed Patient Supports SARS-CoV-2 Viral Reservoir Hypothesis.Semantic proximity Read ↗

Year-long COVID-19 infection reveals within-host evolution of SARS-CoV-2 in a patient with B cell depletionSemantic proximity Read ↗

HIV-1 and SARS-CoV-2: Patterns in the evolution of two pandemic pathogens.Semantic proximity Read ↗

What Has SARS-CoV-2 Taught Us About Evolution?Semantic proximity Read ↗

Intra-host SARS-CoV-2 diversity in immunocompromised people living with HIV provides insight into the evolutionary trajectory of SARS-CoV-2.Semantic proximity Read ↗

SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanismsSemantic proximity Read ↗

Emergence of neutralizing antibodies associates with clearance of SARS-CoV-2 during HIV-mediated immunosuppressionSemantic proximity Read ↗

Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient: a source of immune escape variantsSemantic proximity Read ↗

Intra-host viral populations of SARS-CoV-2 in immunosuppressed patients with hematologic cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.