Article
HIV-1 and SARS-CoV-2: Patterns in the evolution of two pandemic pathogens.
Cell host & microbe - 14 Jul 2021
Fischer Will, Giorgi Elena E, Chakraborty Srirupa, Nguyen Kien, Bhattacharya Tanmoy, Theiler James, Goloboff Pablo A, Yoon Hyejin, Abfalterer Werner, Foley Brian T, Tegally Houriiyah, San James Emmanuel, de Oliveira Tulio, Gnanakaran Sandrasegaram, Korber Bette
Abstract excerpt
Humanity is currently facing the challenge of two devastating pandemics caused by two very different RNA viruses: HIV-1, which has been with us for decades, and SARS-CoV-2, which has swept the world in the course of a single year. The same evolutionary strategies that drive HIV-1 evolution are at play in SARS-CoV-2. Single nucleotide mutations, multi-base insertions and deletions, recombination, and variation in...
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