Article

SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunity

2021-09-23

Abstract excerpt

<h4>Summary</h4> Characterizing SARS-CoV-2 evolution in specific geographies may help predict the properties of variants coming from these regions. We mapped neutralization of a SARS-CoV-2 strain that evolved over 6 months from the ancestral virus in a person with advanced HIV disease. Infection was before the emergence of the Beta variant first identified in South Africa, and the Delta variant. We compared early...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d8a789f4-ae36-541d-a3ef-d566f6c8a339
DOI: 10.1101/2021.09.14.21263564

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunityDOI 10.1101/2021.09.14.21263564Read

SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escapeSemantic proximity Read

SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutationsSemantic proximity Read

Mapping the antigenic diversification of SARS-CoV-2Semantic proximity Read

Characterizing SARS-CoV-2 neutralization profiles after bivalent boosting using antigenic cartographySemantic proximity Read

Longitudinal effects of SARS-CoV-2 breakthrough infection on imprinting of neutralizing antibody responsesSemantic proximity Read

Rapid isolation and resolution immune evasion and viral fitness across contemporary SARS-CoV-2 variantsSemantic proximity Read

Dynamics of SARS-CoV-2 VOC neutralization and novel mAb reveal protection against OmicronSemantic proximity Read

Intra-host SARS-CoV-2 diversity in immunocompromised people living with HIV provides insight into the evolutionary trajectory of SARS-CoV-2.Semantic proximity Read

Infection with the SARS-CoV-2 Delta Variant is Associated with Higher Infectious Virus Loads Compared to the Alpha Variant in both Unvaccinated and Vaccinated IndividualsSemantic proximity Read

Drivers of adaptive evolution during chronic SARS-CoV-2 infectionsSemantic proximity Read

B cell maturation restored ancestral germlines to control Omicron BA.2.86Semantic proximity Read

Emergence of neutralizing antibodies associates with clearance of SARS-CoV-2 during HIV-mediated immunosuppressionSemantic proximity Read