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Article

The susceptibility of single nucleotide polymorphisms located within co-stimulatory pathways to systemic lupus erythematosus.

Frontiers in immunology - 1 Jan 2023

Chen Ding-Ping, Lin Wei-Tzu, Hsu Fang-Ping, Yu Kuang-Hui

Abstract excerpt

Introduction: Autoimmune diseases result from the loss of immune tolerance, and they exhibit complex pathogenic mechanisms that remain challenging to effectively treat. It has been reported that the altered expression levels of co-stimulatory/inhibitory molecules will affect the level of T/B cell activation and lead to the loss of immune tolerance. Methods: In this study, we evaluated the gene polymorphisms of...

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Identifiers

PMID: 38361527
DOI: 10.3389/fimmu.2023.1331796
PMCID: PMC10867627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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