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Article

Investigation of the association between the genetic polymorphisms of the co-stimulatory system and systemic lupus erythematosus.

Frontiers in immunology - 1 Jan 2022

Chen Ding-Ping, Lin Wei-Tzu, Yu Kuang-Hui

Abstract excerpt

Human leukocyte antigen genes have been shown to have the strongest association with autoimmune disease (AD). However, non-HLA genes would be risk factors of AD. Many genes encoding proteins that are related to T- and B-cell function have been identified as susceptibility genes of systemic lupus erythematosus (SLE). In this study, we explored the correlation between SLE and the genetic polymorphisms of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36189300
DOI: 10.3389/fimmu.2022.946456
PMCID: PMC9521740

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