Article
Identifying genetic susceptibility to Aspergillus fumigatus infection using collaborative cross mice and RNA-Seq approach.
Animal models and experimental medicine - 1 Feb 2024
Yosief Roa'a H S, Lone Iqbal M, Nachshon Aharon, Himmelbauer Heinz, Gat-Viks Irit, Iraqi Fuad A
Abstract excerpt
BACKGROUND: Aspergillus fumigatus (Af) is one of the most ubiquitous fungi and its infection potency is suggested to be strongly controlled by the host genetic background. The aim of this study was to search for candidate genes associated with host susceptibility to Aspergillus fumigatus (Af) using an RNAseq approach in CC lines and hepatic gene expression. METHODS: We studied 31 male mice from 25 CC lines at...
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