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Article

Quantitative trait locus (QTL) mapping reveals a role for unstudied genes in Aspergillus virulence.

PloS one - 29 Apr 2011

Christians Julian K, Cheema Manjinder S, Vergara Ismael A, Watt Cortney A, Pinto Linda J, Chen Nansheng, Moore Margo M

Abstract excerpt

Infections caused by the fungus Aspergillus are a major cause of morbidity and mortality in immunocompromised populations. To identify genes required for virulence that could be used as targets for novel treatments, we mapped quantitative trait loci (QTL) affecting virulence in the progeny of a cross between two strains of A. nidulans (FGSC strains A4 and A91). We genotyped 61 progeny at 739 single nucleotide...

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Identifiers

PMID: 21559404
DOI: 10.1371/journal.pone.0019325
PMCID: PMC3084825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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