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Article

Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection.

Genome research - 1 Aug 2011

Durrant Caroline, Tayem Hanna, Yalcin Binnaz, Cleak James, Goodstadt Leo, de Villena Fernando Pardo-Manuel, Mott Richard, Iraqi Fuad A

Abstract excerpt

The Collaborative Cross (CC) is a genetic reference panel of recombinant inbred lines of mice, designed for the dissection of complex traits and gene networks. Each line is independently descended from eight genetically diverse founder strains such that the genomes of the CC lines, once fully inbred, are fine-grained homozygous mosaics of the founder haplotypes. We present an analysis of 120 CC lines, from a...

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Share to Aspergillosis
Share to Aspergillus fumigatus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Crosses, Genetic

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Share to Mice, Inbred Strains

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Source

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Identifiers

PMID: 21493779
DOI: 10.1101/gr.118786.110
PMCID: PMC3149491

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