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Article

Container-aided integrative QTL and RNA-seq analysis of Collaborative Cross mice supports distinct sex-oriented molecular modes of response in obesity.

BMC genomics - 3 Nov 2020

Binenbaum Ilona, Atamni Hanifa Abu-Toamih, Fotakis Georgios, Kontogianni Georgia, Koutsandreas Theodoros, Pilalis Eleftherios, Mott Richard, Himmelbauer Heinz, Iraqi Fuad A, Chatziioannou Aristotelis A

Abstract excerpt

BACKGROUND: The Collaborative Cross (CC) mouse population is a valuable resource to study the genetic basis of complex traits, such as obesity. Although the development of obesity is influenced by environmental factors, underlying genetic mechanisms play a crucial role in the response to these factors. The interplay between the genetic background and the gene expression pattern can provide further insight into...

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Identifiers

PMID: 33143653
DOI: 10.1186/s12864-020-07173-x
PMCID: PMC7640698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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