Article
Germline predisposition for clonal hematopoiesis.
Seminars in hematology - 1 Feb 2024
Kubota Yasuo, Viny Aaron D
Abstract excerpt
Clonal hematopoiesis (CH) is an entity hallmarked by skewed hematopoiesis with persistent overrepresentation of cells from a common stem/progenitor lineage harboring single-nucleotide variants and/or insertions/deletions. CH is a common and age-related phenomenon that is associated with an increased risk of hematological malignancies, cardiovascular disease, and all-cause mortality. While CH is a term of the...
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