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Clonal hematopoiesis and cardiovascular disease in cancer patients and survivors.

Thrombosis research - 1 May 2022

Fuster José J

Abstract excerpt

Cancer genomes have long been known to carry a high number of somatic mutations distributed across many genes. However, recent sequencing studies have unveiled that non-cancerous cells also carry a considerable number of somatic mutations, which are acquired continuously through the lifespan. Accordingly, the pathophysiological relevance of somatic mutagenesis beyond cancer has become a topic of intensive...

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PMID: 36210552
DOI: 10.1016/j.thromres.2021.12.009

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