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Article

Clonal Hematopoiesis

1 Jul 2018

Abstract excerpt

The most important prognostic factor for atherosclerotic cardiovascular disease is age, independent of all other recognized risk factors. Recently, exome sequence analyses showed that somatic mutations in blood cells, a process termed clonal hematopoiesis, are common and increase in prevalence with age, with at least 1 in 10 adults older than 70 years affected. Carriers of clonal hematopoiesis have been shown to...

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PMID: 29987111
DOI: 10.1161/circgen.118.001926

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