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Article

Causes and consequences of clonal hematopoiesis.

Blood - 28 Dec 2023

Weeks Lachelle D, Ebert Benjamin L

Abstract excerpt

ABSTRACT: Clonal hematopoiesis (CH) is described as the outsized contribution of expanded clones of hematopoietic stem and progenitor cells (HSPCs) to blood cell production. The prevalence of CH increases dramatically with age. CH can be caused by somatic mutations in individual genes or by gains and/or losses of larger chromosomal segments. CH is a premalignant state; the somatic mutations detected in CH are the...

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Identifiers

PMID: 37931207
DOI: 10.1182/blood.2023022222
PMCID: PMC10862247

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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