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LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium

30 Jan 2024

Abstract excerpt

ABSTRACT Daptomycin (DAP) is often used as a first-line therapy to treat vancomycin-resistant Enterococcus faecium infections, but emergence of DAP non-susceptibility threatens the effectiveness of this antibiotic. Moreover, current methods to determine DAP minimum inhibitory concentrations (MICs) have poor reproducibility and accuracy. In enterococci, DAP resistance is mediated by the LiaFSR cell membrane stress...

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PMID: 38289081
DOI: 10.1128/aac.01069-23

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faeciumPMID 38289081Read ↗

LiaX is a surrogate marker for cell-envelope stress and daptomycin non-susceptibility in <i>Enterococcus faecium</i>Semantic proximity Read ↗

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