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Article

Evaluation of Immunohistochemical Expression of ALK-1 in Gliomas, WHO Grade 4 and Its Correlation with IDH1-R132H Mutation Status.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2024

Khairy Rasha Ahmed, Momtaz Eman Mohamed, Abd El Aziz Ahmed Mahmoud, Shibel Passant Essam Eldin

Abstract excerpt

BACKGROUND: Glioblastoma (GB), a grade 4 glioma is the most common primary malignant brain tumor in adults. Recently, the mutation status of isocitrate dehydrogenase (IDH) has been crucial in the treatment of GB. IDH mutant cases display a more favorable prognosis than IDH-wild type ones. The anaplastic lymphoma kinase (ALK) is expressed as a receptor tyrosine kinase in both the developing central and peripheral...

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Identifiers

PMID: 38285799
DOI: 10.31557/APJCP.2024.25.1.317
PMCID: PMC10911728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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