Article
[Expression of isocitrate dehydrogenase 1 gene R132H and its diagnostic application in glioma].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Mar 2011
PIAO Yue-shan, LU De-hong, ZHANG Xiao-juan, TANG Guo-cai, YANG Hong
Abstract excerpt
OBJECTIVE: To investigate the immunohistochemical expression of isocitrate dehydrogenase 1 gene (IDH1) R132H in glioma and its diagnostic utility. METHODS: Immunohistochemical study of IDH1R132H expression was performed on formalin-fixed paraffin-embedded tissue samples of 75 gliomas, including 33 cases of grade II, 20 cases of grade III and 22 cases of grade IV tumors. Six cases of pilocytic astrocytoma and 12...
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