Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IDH mutation analysis in gliomas as a diagnostic and prognostic biomarker.

British journal of neurosurgery - 1 Aug 2013

Kurian K M, Haynes H R, Crosby C, Hopkins K, Williams M

Abstract excerpt

INTRODUCTION: There is a high rate of IDH1/2 mutations in low grade gliomas and in high grade gliomas deriving from them. IDH analysis of gliomas is a novel method of classification and an independent prognostic marker. We compared antibody and sequencing methods for the detection of IDH mutations. METHOD: 88 samples from 74 patients were identified. For immunohistochemistry: sections were stained with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytoma
Share to Biomarkers, Tumor
Share to Central Nervous System Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioblastoma

Share to Glioma

Share to Immunohistochemistry

Share to Isocitrate Dehydrogenase

Share to Neoplasm Grading

Source

Identifiers

PMID: 23451940
DOI: 10.3109/02688697.2013.771139

Genes

IDH1
IDH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IDH mutation analysis in gliomas as a diagnostic and prognostic biomarker.PMID 23451940Read ↗

Determining IDH-Mutational Status in Gliomas Using IDH1-R132H Antibody and Polymerase Chain ReactionSemantic proximity Read ↗

IDH mutations: genotype-phenotype correlation and prognostic impact.Semantic proximity Read ↗

Comparative study of IDH1 mutations in gliomas by immunohistochemistry and DNA sequencing.Semantic proximity Read ↗

Expanding the spectrum of IDH1 mutations in gliomas.Semantic proximity Read ↗

IDH1 and IDH2 mutations, immunohistochemistry and associations in a series of brain tumors.Semantic proximity Read ↗

Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors.Semantic proximity Read ↗

An Analysis of the Prognostic Value of IDH1 (Isocitrate Dehydrogenase 1) Mutation in Polish Glioma PatientsSemantic proximity Read ↗

The clinical use of IDH1 and IDH2 mutations in gliomasSemantic proximity Read ↗

Immunohistochemical analysis of 1844 human epithelial and haematopoietic tumours and sarcomas for IDH1R132H mutation.Semantic proximity Read ↗

Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis.Semantic proximity Read ↗

Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma.Semantic proximity Read ↗

Comparison of immunohistochemistry, DNA sequencing and allele-specific PCR for the detection of IDH1 mutations in gliomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.