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Article

Cholesterol associated genetic risk score and acute coronary syndrome in Czech males.

Molecular biology reports - 22 Jan 2024

Hubacek Jaroslav A, Adamkova Vera, Lanska Vera, Staněk Vladimir, Mrázková Jolana, Gebauerová Marie, Kettner Jiri, Kautzner Josef, Pitha Jan

Abstract excerpt

BACKGROUND: Despite a general decline in mean levels across populations, LDL-cholesterol levels remain a major risk factor for acute coronary syndrome (ACS). The APOB, LDL-R, CILP, and SORT-1 genes have been shown to contain variants that have significant effects on plasma cholesterol levels. METHODS AND RESULTS: We examined polymorphisms within these genes in 1191 controls and 929 patients with ACS. Only...

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Identifiers

PMID: 38252350
DOI: 10.1007/s11033-023-09128-3
PMCID: PMC10803395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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