Article
Effect of SORT1, APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II.
Lipids in health and disease - 26 Apr 2016
Shahid Saleem Ullah, ᅟ Shabana, Cooper Jackie A, Beaney Katherine E, Li Kawah, Rehman Abdul, Humphries Stephen Eric
Abstract excerpt
BACKGROUND: Many SNPs have been identified in genes regulating LDL-C metabolism, but whether their influence is similar in subjects from different ethnicities is unclear. Effect of 4 such SNPs on LDL-C and coronary heart disease (CHD) was examined in Pakistani subjects and was compared with middle aged UK men from Northwick Park Heart Study II (NPHSII). METHODS: One thousand nine hundred sixty-five (1770 non CHD,...
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