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Article

Genetic risk analysis of coronary artery disease in Pakistani subjects using a genetic risk score of 21 variants.

Atherosclerosis - 1 Mar 2017

Shahid Saleem Ullah, Shabana, Cooper Jackie A, Beaney Katherine E, Li Kawah, Rehman Abdul, Humphries Steve E

Abstract excerpt

BACKGROUND AND AIMS: Conventional coronary artery disease (CAD) risk factors like age, gender, blood lipids, hypertension and smoking have been the basis of CAD risk prediction algorithms, but provide only modest discrimination. Genetic risk score (GRS) may provide improved discrimination over and above conventional risk factors. Here we analyzed the genetic risk of CAD in subjects from Pakistan, using a GRS of...

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Source

Identifiers

PMID: 28167353
DOI: 10.1016/j.atherosclerosis.2017.01.024

Genes

CAD
APOB
APOE
FTO
LPA
LPL
ACE
APOA5
CETP
CXCL12
GLUL
MIA3
MRAS
NOS3
PCSK9
SMAD3
SORT1

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Genetic risk analysis of coronary artery disease in Pakistani subjects using a genetic risk score of 21 variants.PMID 28167353Read ↗

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