Article
APOA1 and APOB polymorphisms and apolipoprotein concentrations as biomarkers of risk in acute coronary syndrome: Relationship with lipid-lowering therapy effectiveness.
Medicina clinica - 13 Jul 2018
Casillas-Muñoz Fidel, Valle Yeminia, Muñoz-Valle José Francisco, Martínez-Fernández Diana Emilia, Reynoso-Villalpando Gabriela Lizet, Flores-Salinas Héctor Enrique, Llamas-Covarrubias Mara Anaís, Padilla-Gutiérrez Jorge Ramón
Abstract excerpt
BACKGROUND AND OBJECTIVE: Lipid metabolism alterations contribute to acute coronary syndrome (ACS). rs670, rs5070 and rs693 polymorphisms have shown to modify the risk of cardiovascular disease. Apolipoprotein A-I (ApoA-I) plays a major role in reverse cholesterol transport; apolipoprotein B (ApoB) contributes to accumulation of cholesterol in the plaque. The aim of this study was to investigate the association...
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