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Article

Polygenic hypercholesterolemia: examples of GWAS results and their replication in the Czech-Slavonic population.

Physiological research - 5 Apr 2017

Hubacek J A, Adamkova V, Lanska V, Dlouha D

Abstract excerpt

Since 2007, the year of their first widespread use, genome-wide association studies (GWAS) have become the "gold standard" for the detection of causal genes and polymorphisms in all fields of human medicine. Cardiovascular disease (CVD), one of the major causes of morbidity and mortality, is no exception. The first GWAS focused on hypercholesterolemia and dyslipidemia as the major CVD determinants. GWAS confirm...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28379035
DOI: 10.33549/physiolres.933580

Genes

APOB
APOE
CILP2
SORT1
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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