Article
Development and internal validation of a clinical and genetic risk score for rheumatoid arthritis-associated interstitial lung disease.
Rheumatology (Oxford, England) - 1 Jan 2025
Wheeler Austin M, Baker Joshua F, Riley Thomas, Yang Yangyuna, Roul Punyasha, Wysham Katherine D, Cannon Grant W, Kunkel Gary, Kerr Gail, Ascherman Dana P, Monach Paul, Reimold Andreas, Poole Jill A, Merriman Tony R, Mikuls Ted R, England Bryant R
Abstract excerpt
OBJECTIVE: Although clinical and genetic risk factors have been identified for rheumatoid arthritis-associated interstitial lung disease (RA-ILD), there are no current tools allowing for risk stratification. We sought to develop and validate an ILD risk model in a large, multicentre, prospective RA cohort. METHODS: Participants in the Veterans Affairs RA (VARA) registry were genotyped for 12 single nucleotide...
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