Article
Mendelian Randomization Analysis of the Causal Link Between Rheumatoid Arthritis and Interstitial Lung Disease.
Respirology (Carlton, Vic.) - 1 Feb 2026
Zhang Mengyu, Chen Xiao, Zhang Wenqing, Yang Guang, Yin Yunhong, Qu Yiqing
Abstract excerpt
BACKGROUND AND OBJECTIVES: Rheumatoid arthritis (RA) is a systemic autoimmune disease that is often complicated by interstitial lung disease (ILD), one of its most severe extra-articular manifestations. However, whether RA causally contributes to ILD development remains unclear. METHODS: We conducted a two-sample Mendelian randomization (MR) analysis to investigate whether RA has a causal effect on ILD. MR uses...
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