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Article

Novel Association of KLRC4-KLRK1 Gene Polymorphisms with Susceptibility and Progression of Antithyroid Drug-Induced Agranulocytosis.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Jan 2024

He Yayi, Ma Pan, Luo Yuanlin, Gong Xiaojuan, Gao Jiayang, Sun Yuxin, Chen Pu, Zhang Suliang, Tian Yuxin, Shi Bingyin, Zhang Bao

Abstract excerpt

OBJECTIVE: Antithyroid drug (ATD)-induced agranulocytosis (TIA) is the most serious adverse effect during ATD treatment of Graves' disease (GD). Previously, the MICA gene was reported to be associated with TIA. MICA protein is an important ligand for the NKG2D protein, which is encoded by the KLRK1 gene and KLRC4-KLRK1 read-through transcription. This study further investigated the association between KLRC4-KLRK1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38237612
DOI: 10.1055/a-2206-2242

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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