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Article

Association of MICA gene polymorphisms with thionamide-induced agranulocytosis.

Journal of endocrinological investigation - 1 Feb 2021

Ma P, Chen P, Gao J, Guo H, Li S, Yang J, Lai J, Yang X, Zhang B, He Y

Abstract excerpt

BACKGROUND: Thionamide-induced agranulocytosis (TIA), namely antithyroid drug (ATD)-induced agranulocytosis, is one of the most feared adverse effect of ATDs. It is defined as a granulocyte count of less than 0.5 × 109/L after ATD administration. Several studies reported that TIA is associated with human leukocyte antigen (HLA) and nearby genes. Our previous study found that the susceptibility genes of TIA are...

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Identifiers

PMID: 32519199
DOI: 10.1007/s40618-020-01319-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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