Article
Polymorphisms of ATG5 Gene Are Associated with Autoimmune Thyroid Diseases, Especially Thyroid Eye Disease.
Journal of immunology research - 1 Jan 2022
Wang Wen, Yu Zheng-Yao, Song Rong-Hua, He Shuang-Tao, Shi Liang-Feng, Zhang Jin-An
Abstract excerpt
Objective: To explore the association of ATG5 gene polymorphisms with autoimmune thyroid diseases (AITDs) including Hashimoto's thyroiditis (HT) and Graves' illness (GD) as well as their clinical features. Methods: rs6568431, rs548234, and rs6937876 were selected to investigate the correlation of single-nucleotide polymorphisms of ATG5 gene with AITDs. Their frequencies in 824 AITD patients, including 271 HT...
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