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Article

Polymorphisms in Autophagy-Related Gene IRGM Are Associated with Susceptibility to Autoimmune Thyroid Diseases.

BioMed research international - 1 Jan 2018

Yao Qiu-Ming, Zhu Yuan-Feng, Wang Wen, Song Zhen-Yu, Shao Xiao-Qing, Li Ling, Song Rong-Hua, An Xiao-Fei, Qin Qiu, Li Qian, Zhang Jin-An

Abstract excerpt

BACKGROUND: To date, studies have shown that polymorphisms in an autophagy-related gene, IRGM, are linked with different diseases, especially autoimmune diseases. The present study aimed to examine the roles of IRGM polymorphisms in autoimmune thyroid diseases (AITD). METHODS: Three polymorphisms in IRGM gene (rs10065172, rs4958847, and rs13361189) were genotyped in 1569 participants (488 with Graves' disease,...

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Identifiers

PMID: 29992164
DOI: 10.1155/2018/7959707
PMCID: PMC6016217

Genes

IRGM

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