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Article

Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population.

The lancet. Diabetes & endocrinology - 1 Jun 2016

Hallberg Pär, Eriksson Niclas, Ibañez Luisa, Bondon-Guitton Emmanuelle, Kreutz Reinhold, Carvajal Alfonso, Lucena M Isabel, Ponce Esther Sancho, Molokhia Mariam, Martin Javier, Axelsson Tomas, Yue Qun-Ying, Magnusson Patrik K E, Wadelius Mia

Abstract excerpt

BACKGROUND: Drug-induced agranulocytosis is a potentially life-threatening adverse reaction. Genome-wide association studies (GWASs) in ethnic Chinese people in Taiwan and Hong Kong have shown an association between agranulocytosis induced by antithyroid drugs and the HLA alleles HLA-B*38:02 and HLA-DRB1*08:03. We aimed to identify genetic variants associated with antithyroid drug-induced agranulocytosis in a...

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PMID: 27157822
DOI: 10.1016/S2213-8587(16)00113-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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