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Article

Association of an A/C single nucleotide polymorphism in programmed cell death-ligand 1 gene with Graves' disease in Japanese patients.

European journal of endocrinology - 1 Jun 2008

Hayashi Mina, Kouki Tsuyoshi, Takasu Nobuyuki, Sunagawa Sumito, Komiya Ichiro

Abstract excerpt

OBJECTIVE: Programmed cell death-1 (PD-1) and its ligands (PD-L1 and PD-L2) inhibit T-cell proliferation and activation. This inhibition down-regulates the immune responses. The association of a PD-L1 polymorphism with Graves' disease (GD) was studied. DESIGN: The association of an A/C polymorphi...

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Identifiers

PMID: 18322304
DOI: 10.1530/EJE-07-0649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18322304-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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