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Article

Establishment of a forward primers-superposed amplification analysis for accurate aspirin pharmacogenomic measurement.

Scientific reports - 9 Jan 2024

Li Chun-Yan, Yang Ping, Zheng Jie, Zhang Jing, Liu Yi-Qing, Liu Xiao-Quan, Hu Yue, Lan Wen-Jun

Abstract excerpt

Genotyping of gDNA rs12041331 (PEAR1), rs6065 (GP1BA), and rs730012 (LTC4S) can provide systematic guidance on the use of aspirin. However, an accurate, reliable and economical approach to simultaneous detection of the above single nucleotide polymorphisms (SNPs) is not reported. Herein, we designed and substantiated an allele-specific (AS) forward primer-superposed amplification analysis for measurement of the...

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Identifiers

PMID: 38195704
DOI: 10.1038/s41598-024-51458-0
PMCID: PMC10776573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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