Article
Highly specific screening of aspirin resistance-related single-nucleotide polymorphisms using ligase chain reaction strategy.
Talanta - 1 Jan 2025
Li Ying, Zhou Xinchen, Wang Xiangjun, Dong Shuhan, Zhang Zhuo, Jin Zhuo, Jiang Yan, Zhan Xingtong, Yang Shuhui, Wang Helin, Xia Wei, Liu Limei
Abstract excerpt
Aspirin (ASP) is currently the drug of choice for antiplatelet therapy. However, approximately 5%-45 % of patients are resistant to ASP and do not achieve the expected result. At present, a few studies have investigated the correlation between ASP resistance (AR) and single-nucleotide polymorphism (SNP). Traditional detection methods are time-consuming and laborious, affecting the accuracy of personalized...
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