Article
Predicting laboratory aspirin resistance in Chinese stroke patients using machine learning models by GP1BA polymorphism.
Pharmacogenomics - 1 Jan 2024
Liu Jun, Pan Linkun, Wang Sheng, Li Yueran, Wu Yilai, Luan Jiajie, Yang Kui
Abstract excerpt
This study aims to use machine learning model to predict laboratory aspirin resistance (AR) in Chinese stroke patients by incorporating patient characteristics and single nucleotide polymorphisms of GP1BA and LTC4S. 2405 patients were analyzed to measure the Mutation frequency of GP1BA rs6065 and LTC4S rs730012. 112 patients with first-stroke arteriostenosis were prospectively enrolled to establish machine...
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