Article
Simple and accurate visual detection of single nucleotide polymorphism based on colloidal gold nucleic acid strip biosensor and primer-specific PCR.
Analytica chimica acta - 6 Jan 2020
Wang Hai-Bo, Ma Li-Hong, Zhang Ting, Huang Kai-Chen, Zhao Yuan-Di, Liu Tian-Cai
Abstract excerpt
Single nucleotide polymorphism (SNP) was associated with many human diseases, therefore, SNP detection was important for early diagnosis and clinical prognosis. Herein, a simple and accurate method for visual detection SNP sites (A/A, G/G, A/G) in CYP1A1 gene related to cancers based on colloidal gold nucleic acid strip biosensor and primer-specific polymerase chain reaction (PCR) was established. This method...
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