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Article

Ten-Eleven-Translocation Genes in Cancer.

Cancer treatment and research - 1 Jan 2023

Wang Yadong, Wang Xujun, Lu Jun

Abstract excerpt

The Ten-Eleven-Translocation (TET) family of genes, including TET1, TET2, and TET3, play critical roles in the oxidation of 5-methylcytosine marks in both DNA and RNA, thereby regulating the epigenome and epitranscriptome in cells. These genes are frequently mutated in both hematopoietic malignancies and in solid cancers. TET2, in particular, is one of the most frequently mutated genes in clonal hematopoiesis in...

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Identifiers

PMID: 38113007
DOI: 10.1007/978-3-031-45654-1_11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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