Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunohistochemistry Detection of Histone H3 K27M Mutation in Human Glioma Tissue.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Feb 2024

Tarapore Rohinton S, Arain Shehla, Blaine Elizabeth, Hsiung Adam, Melemed Allen S, Allen Joshua E

Abstract excerpt

The presence of the histone 3 (H3) K27M mutation in diffuse midline glioma has implications for diagnosis, prognosis, and treatment, making rapid and accurate H3 K27M characterization vital for optimal treatment. This study evaluated an immunohistochemical assay using a commercially available monoclonal anti-H3 K27M in human central nervous system tumors. H3 K27M-positive glioma specimens were obtained from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioma

Share to Histones

Share to Immunohistochemistry

Share to Mutation

Share to Rabbits

Share to Reproducibility of Results

Source

Identifiers

PMID: 38073235
DOI: 10.1097/PAI.0000000000001176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunohistochemistry Detection of Histone H3 K27M Mutation in Human Glioma Tissue.PMID 38073235Read ↗

Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas.Semantic proximity Read ↗

Clinical, radiologic, and genetic characteristics of histone H3 K27M-mutant diffuse midline gliomas in adultsSemantic proximity Read ↗

Targeting and Therapeutic Monitoring of H3K27M-Mutant Glioma.Semantic proximity Read ↗

H3K27M mutant glioma: Disease definition and biological underpinnings.Semantic proximity Read ↗

Histone H3K27M Mutation Overrides Histological Grading in Pediatric Gliomas.Semantic proximity Read ↗

Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diagnosis and clinical outcomesSemantic proximity Read ↗

Four methods to analyze H3K27M mutation in diffuse midline gliomas.Semantic proximity Read ↗

Characteristics of H3 K27M-mutant gliomas in adults.Semantic proximity Read ↗

Liquid biopsy in H3K27M diffuse midline glioma.Semantic proximity Read ↗

Diffuse high-grade gliomas with H3 K27M mutations carry a dismal prognosis independent of tumor location.Semantic proximity Read ↗

A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas.Semantic proximity Read ↗

Molecular and clinical characterization of H3 K27M-mutant "non-midline" glioblastoma: A case report and literature review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.