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Article

Characteristics of H3 K27M-mutant gliomas in adults.

Neuro-oncology - 1 Aug 2017

Meyronet David, Esteban-Mader Maud, Bonnet Charlotte, Joly Marie-Odile, Uro-Coste Emmanuelle, Amiel-Benouaich Alexandra, Forest Fabien, Rousselot-Denis Cécilia, Burel-Vandenbos Fanny, Bourg Véronique, Guyotat Jacques, Fenouil Tanguy, Jouvet Anne, Honnorat Jérôme, Ducray François

Abstract excerpt

BACKGROUND: Diffuse H3 K27M-mutant gliomas occur primarily in children but can also be encountered in adults. The aim of this study was to describe the characteristics of H3 K27M-mutant gliomas in adults. METHODS: We analyzed the characteristics of 21 adult H3 K27M-mutant gliomas and compared them with those of 135 adult diffuse gliomas without histone H3 and without isocitrate dehydrogenase (IDH) mutation...

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Identifiers

PMID: 28201752
DOI: 10.1093/neuonc/now274
PMCID: PMC5570304

Genes

MGMT
BRAF
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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