Article
Four methods to analyze H3K27M mutation in diffuse midline gliomas.
Pathology, research and practice - 1 Sept 2020
Zhao Huanying, Fang Xiao, Xue Bing
Abstract excerpt
The histone H3 K27M mutation has been frequently reported in the majority of diffuse midline gliomas, which is considered as a prognostic and predictive biomarker. A number of different methods and platforms including pyrosequencing (PSQ), sanger sequencing, immunohistochemistry (IHC), Mass array and NGS (Next Generation Sequencing) have been used to detect H3K27M mutation in diffuse midline gliomas. However,...
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