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Article

Immune checkpoint status and exhaustion-related phenotypes of CD8+ T cells from the tumor-draining regional lymph nodes in breast cancer.

Cancer medicine - 1 Dec 2023

Yilmaz Izel, Tavukcuoglu Ece, Horzum Utku, Yilmaz Kerim Bora, Akinci Melih, Gulcelik Mehmet Ali, Oral Haluk Barbaros, Esendagli Gunes

Abstract excerpt

BACKGROUND: Functional status of T cells determines the responsiveness of cancer patients to immunotherapeutic interventions. Even though T cell-mediated immunity is inaugurated in the tumor-adjacent lymph nodes, peripheral blood has been routinely sampled for testing the immunological assays. The purpose of this study is to determine the immune checkpoint molecule expression and the exhaustion-related phenotype...

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Source

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Identifiers

PMID: 38069525
DOI: 10.1002/cam4.6802
PMCID: PMC10757146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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